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Like in fat tissue, it boosts GLUT4 production there and raises metabolic inefficiency for more energy use

One works through satiety signaling

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Mehta KM, Yeo GW

[4] It is formally categorized as a Sympathomimetic Amine Anorectic. In summary, phentermine simulates a stress-like signal in the appetite-control centers of the brain, which produces reduced hunger and satiety with smaller meal portions