In a double-blind RCT in T2D patients, a single dose of the GLP-1 analogue albiglutide did not impair the -cell response or GH secretion when blood glucose was clamped in the hypoglycemic range ( 2460 h), FFAs represent the key fuel of whole-body energy homeostasis
Yes, but you must carry it in your hand luggage not checked baggage using a validated medical-grade cool bag with a temperature logger, and bring a letter from your trial site confirming its status as a clinical trial medicine
In the main published Phase 2 obesity trial, fatigue was reported by 7% of retatrutide participants and 4% of placebo participants
Knowing when to seek medical evaluation prevents dismissing something that needs attention
Again, you just wrote a book to try to help primary care physicians think through this, but how prepared are primary care physicians now to have this kind of conversation in which we consider seriously lifestyle and what that can accomplish, but also we don't just either rush to the GLP-1 or say no, you don't need that
Ayesha Bryant, MSPH, MD, is a physician, clinical scientist, and associate professor passionate about bridging medical science and everyday health