As the condition progresses, you may notice: Fatigue and weakness Swelling in your feet, ankles, or legs Shortness of breath Nausea and vomiting Loss of appetite Changes in urination (more or less frequent, foamy, or bloody) Difficulty concentrating or confusion To diagnose kidney disease, your doctor may perform the following tests: Blood tests to measure waste product levels Urine tests to check for protein or blood Imaging tests, such as an ultrasound, to visualize your kidneys Kidney biopsy to determine the cause of your kidney problems Treatment for kidney disease depends on the underlying cause and the stage of the condition
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doi: 10.1038/nm.4345 136 WulffelM
In addition to reducing or eliminating the symptoms of B12 deficiency, research suggests that B12 shots may: Reduce stress (7) Support central nervous system function, red blood cell formation, and DNA synthesis (2) Reduce the risk of vision loss from age-related macular degeneration (8) Lower homocysteine levels, which is associated with cardiovascular disease and stroke (9, 10)