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Neuroinflammation 17 , 39 (2020)
doi:10.1016/j.nutres.2011.01.002
The overall molecular properties of orforglipron, molecular weight approximately 529 Da, moderate lipophilicity (cLogP approximately 3.5), and limited hydrogen bond donors and acceptors, place it within the "drug-like" chemical space defined by Lipinski's Rule of Five, although at the upper boundary
It has been observed that prolonged poor prognosis was associated with high expression of CBP/p300
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