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C.MagginiS

ET-1 is the main endothelin generated by the endothelium and is the most important endothelin in the cardiovascular system

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Cellular and Molecular Life Sciences

Another protective agent, P22077, inhibits ubiquitin-specific protease 7, activates p53 and subsequently lowers TFR1 levels, thereby suppressing ferroptosis and protecting the heart from I/R damage (239)

5 Conclusion The family of the ChaC-like enzymes has attracted increasing attention over the past few years