Methods We review surgical outcomes from existing literature and no individual patients are involved, hence there are no relevant patient consent issues, Institutional Review Board involvement, or ethics approval integral to this perspective
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Finally, ongoing or recently completed, yet unpublished, RCTs are expected to provide additional information on the comparative effects of tirzepatide vs other glucose-lowering agents, including dulaglutide (ClinicalTrials.gov registration no
These challenges are material, but they are also not new
While GLP-1 RAs target a wide range of organ systems, their impacts on gastrointestinal motility are widely regarded as a major mechanism by which they exert their metabolic effects
Uccellatore A, Genovese S, Dicembrini I, Mannucci E, Ceriello A