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There are practical reasons too: B can be unstable if mixed with certain other vitamins in solution, and dosing schedules for B deficiency (pernicious anemia, for instance) may differ
In contrast, while Ly boosted WNT3A expression and accelerated primitive streak/MD induction, it resulted in a mixed population that included unwanted mesoderm [1]
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Work going back to 2000 found that -MSH and its C-terminal KPV sequence inhibit the growth of pathogens including Staphylococcus aureus and the yeast Candida albicans , with the lysine and proline residues doing most of that work (Cutuli et al., 2000)