The composition of GHK-Cu is: glycine-histidine-lysine-copper (glycyl-L-histidyl-L-lysinecopper), copper ion Cu2+ is not the yellow color of copper metal, but blue in aqueous solution, so GHK-Cu is also called blue copper peptide
Cu(II) is held in a square-planar coordination sphere by the N-terminal amine, the deprotonated glycyl amide nitrogen and the histidine imidazole, at a stability constant (log K approximately 16.4) close to that of the copper transport site on human serum albumin
As collagen depletion is one of the biggest factors leading to visible signs of aging, this effect has made GHK-Cu a coveted ingredient when it comes to anti-aging solutions
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The rather broad definition of heavy metals may also be applied to toxic metalloids (a chemical element that has properties that include a mixture of those of metals and non-metals), like arsenic, as well as nutritionally-essential trace minerals with potential toxicities at elevated intake or exposure (eg, iron, zinc, or copper)
