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The findings may pave the way toward the development of 15LO1 inhibitors as asthma treatments

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Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity

Mechanistically, we uncovered that breast cancer cells in the LN displayed high levels of interferon-induced gene signatures, including a subpopulation of cancer cells that had MHC-II gene expression and an absence of co-stimulatory molecules ( Figure 2 )