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Together, these limitations explain why FGF21 analogues show strong effects on lipids, adiponectin, and hepatic fat but only modest glycemic responses in people with obesity and type 2 diabetes

This poor prognosis is compounded by the challenging anatomical location that makes early detection difficult and complete surgical excision more complex compared to cutaneous melanoma [6]

This meta-analysis further showed that in the age group of 70 to 79 years, a higher prevalence of PD is noted in Europe, North America, and Australia than in Asia

doi: 10.1016/j.cmet.2008.03.006 108 LiuJCondeKZhangPLilascharoenV

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Its caused by a combination of age, genetics, and hormones