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More than half of the tirzepatide group lost at least 20% of body weight, compared to about a quarter of the semaglutide group

Under FDA guidance documents and Chemical Safety Board recommendations, research-use-only (RUO) designation applies to chemical reagents, biological specimens, and investigational compounds sold exclusively for in vitro studies, animal research models, or mechanistic investigations conducted under controlled laboratory conditions

Coagulated blood vessel walls and a proportion of vessels with fibrin clots (dashed white arrow) (HE, x4 ( c ), x10 ( C ))