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Reporting side effects : If you experience a suspected side effect, report it to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk or via the Yellow Card app

The COR-I trial, involving 1,742 participants over 56 weeks, demonstrated 6.1% average weight loss with Contrave versus 1.3% with placebo (Greenway et al., Obesity, 2010)

Sulfur burps are accompanied by severe abdominal pain, nausea, vomiting, or unexpected weight loss

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Reported positive in December 2025, first Phase 3 readout of the program

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