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21 In head-to-head trials, gastrointestinal effects appeared to be greater with liraglutide than exenatide extended-release (DURATION-6) 13 and albiglutide (HARMONY-7) 17 , but liraglutide-treated patients experienced less nausea than those receiving exenatide twice daily (LEAD-6)

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In April 2025, according to an article published by the Heart Rhythm Society, a recent clinical study, TRANSFORM-AF, found that GLP-1 receptor agonists (GLP-1 RAs), typically used for diabetes, may reduce atrial fibrillation (AF)-related events in patients with both obesity and AF

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