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Large-scale, multicenter Phase III trials with rigorous design, adequate sample sizes, long-term follow-up extending to at least 12 months, and histological endpoints are urgently needed to establish definitive efficacy (83, 88)

In the event of an immediate adverse reaction during intravenous infusion, the administration of the drug should be interrupted immediately and, if possible, the unused remaining liquid should be saved for examination

NNMT and Cancer Elevated NNMT expression has been observed in several forms of cancer, including gastric, pancreatic, renal cell carcinoma, and bladder cancers

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2015 Nov 26;373(22):2103-16

Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M et al (2005) Diversity of the human intestinal microbial flora