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This difference in scope is the central reason the two are discussed as potentially complementary rather than redundant

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Initial absorbance (OD1) at 412 nm was measured

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First, a weighted combination of receiver channels was conducted, followed by removal of motion-corrupted signal averages, frequency and phase drift correction using spectral registration [51], and subspectra alignment before subtraction and signal averaging were performed

[Abstract]2024 Jun 14;5(6):e612