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Abstract The mechanisms underlying obesity-induced insulin resistance remain incompletely understood, as impaired cellular insulin signaling, traditionally considered the primary driver of insulin resistance, does not always accompany impaired insulin action

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Some patients describe hearing or feeling a pop as the tendon tears, and the pain can make it difficult to bear weight or move the leg

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10.1136/heartjnl-2015-308826 98 SuzukiT.YazakiY.VoorsA

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28 For patients who continue with CPAP, there may be incomplete resolution of their apnoea for various reasons, such as suboptimal equipment upkeep

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In gastric cancer, HDAC4 promotes tumor growth by enhancing the autophagic degradation of MEKK3, thereby reducing its stability and favoring cell survival

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