Previous studies suggest that GCL is localized to the chloroplasts and GS is localized both to chloroplasts and cytosol in plant cells (Hell and Bergmann, Arabidopsis suggests that GCL and GS are each encoded by a single gene with alternate transcription start sites leading to either plastid-targeted or cytosolic protein (Wachter et al., 2005)
Mass spectrometry The conversion of GSH into GSSG was monitored by mass spectrometry (Agilent 1290 UPLC/6540 Q-TOF)
It is primarily investigated in models of obesity, muscle wasting (sarcopenia), and metabolic bioenergetics
Diabetes is a leading cause, but infections, vitamin deficiencies, and toxins can also contribute
The oxidative stress and mitochondrial dysfunction during the pathogenesis of diabetic retinopathy
Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application