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Dosing is individualized based on response and side effects, often starting at lower doses than those used in transplant patients

Hepatocyte growth factor protects auditory hair cells from aminoglycosides

M1-like macrophages amplify ferroptotic pressure through ferritinophagy-mediated release of labile Fe + , increased transferrin receptor (TfR1) expression, and restricted ferroportin activity, thereby enriching the tumor microenvironment (TME) with redox-active iron (71)

Nausea, vomiting, diarrhoea, constipation, and abdominal pain affect a significant proportion of patients, particularly during dose escalation

GLP-1 receptor agonists carry a boxed warning about thyroid C-cell tumors based on animal studies with liraglutide

Uma Devi et al