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The epigenetic aging analysis was post hoc, meaning it was run afterwards, inside a trial designed to answer a different question

Novo plans to begin selling its FDA-approved weight-loss pill in the US in January following Oasis 4 trial results showing 13.6% average weight loss over 64 weeks, while Lilly's oral alternative, orforglipron, received expedited FDA review under a new 2025 voucher program and could be approved as soon as March, according to CEO Dave Ricks

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The medication produces best results with consistent moderate deficits, not starvation patterns

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