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In theory, neither the health professionals conducting the studies nor the patients participating in the trials know who is getting the active drug and who is getting the placebo

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While Ozempic is FDA approved for type 2 diabetes and, under the brand name Wegovy, for weight control, it may have off-label uses as well

doi: 10.1016/S0025-6196(12)64862-9

This is when the physical feedback loop kicks in

RoA, route of administration