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5 Chondrocytes exposed to TNF- and IL-1 are key mediators to release matrix metalloproteinases (MMPs), and inhibits the synthesis of extracellular matrix proteins in chondrocytes which are responsible for the degeneration of articular cartilage

Finally, vitamin B12 is crucial for the biochemistry of the nervous system, participating in DNA synthesis, methionine synthesis, methylation reactions, myelin synthesis, and neurotransmitter production (42, 70, 73, 77)

Inflammatory factors were detected using enzyme-linked immunosorbent assay (ELISA)

An older This supplement is often well-tolerated, but there is not enough evidence to support its use

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MMP-7, matrix metalloproteinase 7