For example, reduced levels of SCFAs (like butyrate, which is normally made by good bacteria) can weaken the BBB, making the brain more vulnerable to harmful substances
Cole TA, Zhao H, Collier TJ, Sandoval I, Sortwell CE, Steece-Collier K, Daley BF, Booms A, Lipton J, Welch M, Berman M, Jandreski L, Graham D, Weihofen A, Celano S, Schulz E, Cole-Strauss A, Luna E, Quach D, Mohan A, Bennett CF, Swayze EE, Kordasiewicz HB, Luk KC, Paumier KL (2021) -Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinsons disease
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doi:10.3109/03602532.2011.561353
6 A small crossover trial in healthy adults also found that a single curcumin-containing drink lowered postprandial glucose excursions, suggesting that polyphenol-rich foods may complement dietary GLP-1 strategies, although GLP-1 itself was not measured
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