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Second, the trials allow for flexible dose adjustment, including dose reductions and extension of dose-escalation intervals

Glutathione participates in: neutralising reactive oxygen species supporting detoxification pathways in the liver maintaining intracellular balance It also interacts with enzymes such as glutathione peroxidase, which plays a role in protecting cells from oxidative damage

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Lancet Diabetes Endocrinol 2017;5:355-66.ArticlePubMed 567

To test GRX-dependent oxidation of reduced roGFP2, the reaction was started by adding 50 M GSSG