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Randomized controlled trials, observational studies, meta-analyses, and pharmacovigilance reports evaluating GI adverse effects of GLP-1based therapies were included

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The study found increased risk in both patients with type 2 diabetes and patients using semaglutide for overweight or obesity, but the authors noted that the study was observational and could not prove that semaglutide directly caused NAION

I tell my patients to shoot for 1.2 to 1.6 grams per kilogram while theyre losing weight on a GLP-1. Dr

Instead, wait until the following Saturday (nine-day gap), then continue on Saturdays