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Available online: [Google Scholar] 71.Ayoub W.A., Kumar A.A., Naguib H.S., Taylor H.C

24 This attenuation is dependent on the magnitude of immune activation, because fairly large quantities of circulating IL-1 produce fever and sickness behaviour by bypassing the neural circuits, acting through brain circumventricular organs (including the area postrema) and via other humoral mechanisms (Figure 1)

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