2 Global epidemiology and SLD progression to HCC HCC is a significant global health threat, ranking as the fourth most common cancer and the second leading cause of cancer-related mortality worldwide (Ma et al., 2024
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Studies show potential for treating NASH progression through direct hepatic GLP-1 receptor activation
Peptide therapeutics are particularly well suited to this paradigm, as their endogenous nature often allows direct linkage between receptor engagement and downstream physiological effects
Nausea, diarrhea, vomiting, and constipation commonly occur within the first month of starting.[ref][ref] Note that for many people, gastrointestinal side effects seem to be dose-related
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