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Burping is a common digestive side effect experienced by patients taking tirzepatide (Mounjaro, Zepbound), a dual GIP and GLP-1 receptor agonist approved for type 2 diabetes and chronic weight management

It activates GLP-1 receptors in the brain and gut, reducing appetite, slowing gastric emptying, and improving insulin sensitivity

and G.B.H., P30AG050886 to D.B.A

J Comput Aided Mol Des 40 , 95 (2026)