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10.3390/toxics13070594 14 EngstrmA.WintzellV.MelbyeM.SvanstrmH.EliassonB.GudbjrnsdottirS.et al (2024)
The investigators examined data from 92,497 users of GLP1-RA and 2,484,408 users of DPP-4i
A Phase 2 trial by Metabolic Pharmaceuticals found that while the compound was well-tolerated, it did not produce statistically significant weight loss versus placebo at the doses tested
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In a 48-week, placebo-controlled phase-2 trial (338 participants) reported by Lilly, the highest dose achieved a mean weight reduction of 24.2% (about 57.8 lb) at the end of treatment
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