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They are: 98% more likely to have a psychiatric disorder 195% higher risk of depression at a 9X higher risk of pancreatitis 3.7X more likely to have gastroparesis 4X higher risk of developing a bowel obstruction The combination of a high incidence of side effects, a lack of patient education, an increased risk for both physical and mental health disorders, and the rising demand for GLP-1s has created the perfect storm for patients who find themselves experiencing debilitating side effects without the knowledge of how to control them

doi: 10.1016/0196-9781(87)90163-x