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Weight loss associated with semaglutide use is linked to improved reproductive measures in PMOS: a proof-of-concept analysis

In a nutshell, the nucleus of every cell contains the complete genome, but only certain genes remain essential for that cell to function

the mechanism seems unclear: Drucker explains that GLP-1 doesnt directly get into the brain to a meaningful extent, and how it communicates with the brain is is not well understood in the magic that we see. Given the impact of GLP-1 on appetite control, this seems like a glaring gap in understanding or rather, an important opportunity for future study

November 11, 2023

Compliance with ethical standards Conflict of interest The authors declare that they have no conflict of interest

doi: 10.1016/j.amjmed.2009.11.019 54 RosenstockJKlaffLJSchwartzSNorthrupJHolcombeJHWilhelmKet al