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It does not matter when you take a substance, if it is prohibited in-competition and it is found in your system you may face a ban

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Those observations are included here only to summarize research context

A further aggravation of experimental conditions in chronic unpredictable stress procedure led to a failure of imipramine activity (30 mg), whereas NaBPC157 (10 g, 10 ng) dose-dependently improved the mobility in chronically stressed rats

Case studies highlight how this approach can work in real life