ATM-deficient mice, worms, and cell models demonstrated accumulation of cytoplasmic DNA, hyperactivation of PARP1, and low NAD + levels 111,288
S.KisbyG
Moreover, upregulation of gastric COX-1 protein and NF-B gene due to ulcer induction were abolished by both omeprazole and NPW treatments
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Biochem Pharmacol 79(7):939947 Kim YM, Lee JJ, Park SK, Lim SC, Hwang BY, Lee CK, Lee MK (2007) Effects of tributyltin acetate on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells
More importantly, the nanocomplex retained the intrinsic bioactivity of EGCG [45, 46]