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Besides, as it reacts with SUMO1-PA/SUMO3-PA probes, suggesting it to be active as exo-isopeptidase acting at the distal end of SUMO2/3 chains terminated by SUMO2/3 or SUMO1

however, it is possible that the mAb binding to the C-terminal FLAG tag of this particular macrocycle hinders the macrocyclic portion from interacting with Met

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doi:10.17352/ojabc.000024 ^ Sharkey T.D

10.1007/s10157-012-0621-7 107 SikorskaD.PawlaczykK.BaumE.Wanic-KossowskaM.CzepulisN.LuczakJ.et al (2019)