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Myth #4: Eating Less Is Always Better Severe calorie restriction may worsen fatigue, nutrient deficiencies, and muscle loss

Exendin-4 differs from human GLP-1 by about 50% of its amino acids, importantly having a glycine instead of alanine at the N-terminus (making it DPP-4 resistant) ( [46] )

GLP-1 stands for glucagon-like peptide-1, a naturally occurring hormone released in the gut after you eat

Disclaimer: This product is not intended to diagnose, treat, cure or manage any disease

doi: 10.1002/hep.32272 [DOI] [PMC free article] [PubMed] [Google Scholar] 9.Grant BF, Goldstein RB, Saha TD, et al

This represents a boundary case where regulatory flexibility, combined with restricted labeling, enabled approval despite pharmacokinetic constraints that would preclude approval for most indications (Melmed et al., 2015)