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Fibroblast cultures were established from parenchymal lung tissue by an explant technique as previously described [24]

Similarly, genetic deletion of floxed Gpx4 in Pfa1 cells 22 increased endogenous S 0 levels, including glutathione hydropersulfide and hydrotrisulfide (GSSH and GSSSH, respectively) (Fig

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This dual action, promoting the breakdown of existing fat while simultaneously slowing the creation of new fat, makes the theoretical mechanism appealing

GPX7 can utilize the H 2 O 2 produced by Ero1 to accelerate the oxidative folding process of proteins in vitro and in vivo (Bosello-Travain et al., 2013

[1] Ozempic is a once-weekly injection