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Understanding and following these three phases is essential for the HCG diets success

[23] The duration of therapy (number of weeks or months of injections) is also determined on a case-by-case basis

This is uncommon but might contribute to symptoms in some patients, particularly those taking certain medications like diuretics

Shortening the frequency between shots

This timeline matches B12 pharmacokinetics: intramuscular methylcobalamin reaches peak serum concentration at 8-12 hours, but tissue saturation (particularly in the liver and nervous system) occurs over 48-72 hours as the vitamin is transported into cells and converted to active coenzyme forms (Andrs et al., 2018)

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