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New modalities for challenging targets in drug discovery

Results GSH synthesis is required for the survival of adult animals To better understand the importance of GSH in adult mammals, we developed an inducible, whole-body Gclc KO mouse by breeding the Gclc f/f mouse strain 30 with the Rosa26-CreERT2 mouse strain 31

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Most people experience mild nausea during this phase, but its typically manageable

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