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Two commonly referenced comparison compounds are semaglutide and tirzepatide, which represent single receptor and dual receptor incretin agonist designs respectively

Consult your doctor or pharmacist before making any changes to your medication routine, especially while you are still titrating up

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The M6 (Macrovascular & Microvascular Morbidity and Mortality) study followed 3,932 adults with obesity and type 2 diabetes treated at Cleveland Clinic for up to 10 years : 1,657 had metabolic surgery (sleeve gastrectomy or gastric bypass) and 2,275 used GLP-1 receptor agonists (e.g., liraglutide, dulaglutide, exenatide, semaglutide, tirzepatide)