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Materials and methods The study follows the PRISMA statement [16] and Cochrane Handbook [17]

The mean estimated treatment difference of changes was 0.21% points (95% confidence interval, 0.39 to 0.02

[9,10,11] Acetaminophen-related liver toxicity is responsible for about half of all cases of acute liver failure in the United States.[12] Acetaminophen toxicity is the #1 reason for liver transplants in the USA, and the #2 reason for liver transplants worldwide.[13] This risk is especially high in people who drink alcohol: Check out my article & video on The Hangover Remedy That Can Kill You. In summary: Paracetamol is mean to the liver, and it doesnt take much more than the recommended dose to cause major harm

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