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This sustained weight loss demonstrates the long-term advantages of including Mounjaro in a weight management plan

The initial oral semaglutide dosage is typically 3 mg once daily

Contact your healthcare provider immediately if you experience: Severe, persistent diarrhea preventing adequate hydration Clinical signs of dehydration (dizziness, dry mouth, dark urine, orthostatic symptoms) Blood in stool or severe abdominal pain Fever accompanying diarrhea Inability to maintain fluid intake due to concurrent vomiting Clinical reports have documented cases of acute kidney injury from severe volume depletion due to excessive diarrhea on GLP-1 therapy

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CNS Drugs 33:209223

Other key brain cell populations that respond to GLP-1 include neurons in the area postrema (AP) (Kawatani et al