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This results in both acute GH secretion and, with repeated stimulation, upregulation of GH gene transcription and somatotroph proliferation in experimental models

The latter has a larger capacity than PCr degradation and provides ATP primarily via the breakdown of glycogen in the glycolytic pathway, resulting in excessive pyruvate production

doi: 10.1007/s00595-007-3706-2

Design After 4-week run-in period and stratification according to previous statin therapy, patients were randomized to 6-month, double-blind treatment with ALC or placebo added-on simvastatin

doi: 10.1007/s00384-020-03648-1 179 Arteaga-MullerGYFlores-TrevioSBocanegra-IbariasPRobles-EspinoDGarza-GonzlezEFabela-ValdezGCet al