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The risk of MACE was reduced by 12% (HR 0.88, 95% CI 0.840.94) with GLP-1RAs and by 11% (HR 0.89, 95% CI 0.830.96) with SGLT2is compared with that in placebo groups, suggesting that GLP-1RAs and SGLT2is reduce the risk of MACE to a similar extent

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doi: 10.1007/s00431-009-1058-1

Sixth, stratified analyses resulted in some groups with a relatively low number of participants and events, where risk estimates should be considered as exploratory findings