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A 2023 study in JAMA found significantly increased risk of gastrointestinal complications including gastroparesis in patients using GLP-1 drugs for weight loss

Bai R, Guo J, Ye X, Xie Y, Xie T

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Lunger, F

As there is scant research investigating the sexual side effects of semaglutide, all current explanations are purely speculation that necessitate further exploration in basic science research and clinical trials." Journal reference: Able, C., Liao, B., Saffati, G., et al