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In the SURMOUNT 1 Trial (pooling doses), total lean mass was reduced by 8.5 absolute percentage points [15]

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Patients initiating GLP-1 RA treatment (semaglutide, liraglutide, tirzepatide) were propensity scorematched (1:1) with RA controls not receiving GLP-1 RA therapy, balancing demographics, BMI categories, cardiovascular comorbidities, immunosuppressive therapies, and cardiometabolic medications

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Will there still be unhealthy people, with unhealthy habits