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Metformin improves insulin sensitivity while semaglutide suppresses appetite, potentially creating complementary effects

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Ongoing surveillance is only recommended if extensive gastric atrophy, intestinal metaplasia, or additional risk factors are identified

At a Glance Causes: Fatigue on semaglutide may stem from reduced calorie intake, loss of muscle, dehydration from GI side effects, or, less commonly, blood sugar drops

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