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doi: 10.1185/03007991003672551 33 PratleyRENauckMBaileyTMontanyaECuddihyRFilettiSet al

If symptoms are persistent but manageable: Consider a temporary dose reduction of one step in the escalation schedule

This broader activity is one reason researchers are interested in its potential metabolic effects

doi: 10.1016/j.phrs.2018.03.003 158 LiLXiongQZhaoJLinXHeSWuNet al

Building on striking phase 2 data which showed mean body weight reductions of approximately 24% at the highest dose over 48 weeks retatrutide simultaneously targets GLP-1, GIP, and glucagon receptors, potentially offering a more powerful metabolic effect than existing treatments