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Replacement of Glu170 in E170A/K resulted in a 5060% decrease of the k cat app values for GSH but had a rather minor effect on the k cat app (HEDS) values (Fig

For inclusion, patients required at least one HbA1c or weight measurement in the 90 days before the index date (baseline measurement) and a corresponding measurement at 180 days and/or 365 days after the index date (follow-up measurement

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