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For instance, while semaglutide promotes fat loss, TRT can help ensure that muscle mass is maintained or even increased during the weight-loss process

In my experience reviewing the research, the glucagon receptor activation is the part that stands out

Ethics declarations Funding This work was supported by the National Natural Science Foundation of China (82103475), Hebei Province Natural Science Foundation (H2023307028, H2024206056), the Medical Science Research Project of Hebei Provincial Health Commission (20240370), Hebei Province Medical Adaptation Technology Tracking Project (GZ2024002), and Hebei Province Government-Funded Clinical Medicine Excellent Talent Training Program (ZF2025013)

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