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Limitations of the therapeutic use of superoxide dismutase Due to the instability, high immunogenicity, low cellular uptake and less in vivo circulation of the half-life of superoxide dismutase, their clinical use as therapeutic agents is very limited
Free Radic Biol Med 53(9):17481759 Korkmaz-Icz S, Atmanli A, Radovits T, Li S, Hegeds P, Ruppert M, Brlecic P, Yoshikawa Y, Yasui H, Karck M, Szab GJ (2016) Administration of zinc complex of acetylsalicylic acid after the onset of myocardial injuryprotects the heart by upregulation of antioxidant enzymes
J Invest Dermatol (2015) 135(6):151020
SimonettiOBacchettiTFerrettiGMolinelliERizzettoGBellachiomaLet al
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