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[18] [19] One member who had supported the earlier substances broke ranks here, describing concern about potentially dangerous downstream consequences, and members raised a mechanistic worry that endorphin release resembled the reward-pathway activity of addictive drugs

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From this analysis, we also found that setting a fixed overlap of 1 Da between adjacent mass windows assured optimal quantification of precursors with m / z values at the edges of isolation windows (Supplementary Fig

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